Gluco6 is a simple one-capsule-a-day formula, and unlike many blood sugar supplements it shows a full Supplement Facts label on its order page. Its strongest ingredient on paper is chromium, at a high 1 mg dose, alongside cinnamon, gymnema, green tea extract and L-arabinose, all of which have some research behind them. The research is weak, though, the herb amounts are hidden inside a 525 mg blend, and the sales copy makes weight loss and "ditch your meds" promises that no supplement can keep. It suits adults with mildly raised blood sugar who have spoken to their doctor, not people looking to replace treatment.
What we like
- Full label shown on the order page
- One capsule a day
- One-time payment, no subscription
- 60-day refund that accepts opened bottles
Keep in mind
- Herb amounts hidden in a 525 mg blend
- Can add to the effect of diabetes medicines
- "No stimulants" badge, but contains theacrine and theobromine
- Weight-loss and "ditch your meds" claims are overstated
Check Gluco6 price on the official site →Opens the brand's official website · money-back guarantee
The bottle says Good Mix Naturals Gluco 6 Advanced Formula; the website calls it Gluco6. It is the same product.
Gluco6 is a daily capsule sold to support healthy blood sugar. The sales page highlights six ingredients (Sukre, chromium, cinnamon, TeaCrine, gymnema and green tea), but the label image on the same page lists more: chromium 1 mg, vitamin D3 2,000 IU and vitamin B1 100 mg, plus a 525 mg blend of L-arabinose, theobromine, green tea extract, eleuthero, theacrine, cassia cinnamon and gymnema. You take one capsule in the morning. It is sold through gluco6.com at $39 to $69 per bottle as a one-time payment, with a 60-day money-back guarantee. This review covers the label, the evidence for each ingredient, the price, the refund fine print and, most important, the safety points for anyone already on diabetes medicine.
First, a word about blood sugar
High blood sugar rarely causes symptoms early on, which is why many people find out about prediabetes or type 2 diabetes from a routine blood test. If you have not had an A1C or fasting glucose test recently, start there: it tells you where you stand and gives you a number to compare against later.
If you already have diabetes, your medicine is doing a job that no supplement has been shown to do. NCCIH is blunt about this: it is very important not to replace diabetes treatment with an unproven product, and the FDA warns about products that promise to replace diabetes medicine. Gluco6 is a dietary supplement, not a treatment for diabetes. Never lower or stop metformin, insulin or any other diabetes drug without your doctor, and watch for signs of low blood sugar (shakiness, sweating, confusion, a racing heart) if you add a supplement like this one.
What is inside Gluco6?
We read the Supplement Facts panel from the label image on the official order page (it is marked "sample", so compare it with the bottle you receive). Here is each ingredient next to what the research actually supports.
| Ingredient (per capsule) | What the brand says | What research supports |
|---|---|---|
| Chromium (as chromium niacinate), 1 mg | Enhances insulin sensitivity, helps burn fat | A 2022 review of 16 trials suggested small improvements in HbA1c and fasting glucose in type 2 diabetes. NCCIH calls the evidence weak. 1 mg is about 28 times the daily value. |
| Vitamin D3, 50 mcg (2,000 IU) | Not described on the sales page | Useful if you are low. In diabetes reviews the effect on blood sugar was small and below what doctors consider meaningful. |
| Vitamin B1 (thiamine), 100 mg | Not described on the sales page | Essential vitamin; no good evidence that extra thiamine lowers blood sugar in people who are not deficient. |
| Sukre™ (L-arabinose) | "Manipulates glucose movement out of the bloodstream" | L-arabinose slows the enzyme that digests table sugar. A small Japanese study cited by the brand found a lower glucose rise when it was eaten with a sucrose-containing food. |
| Green tea extract (98% polyphenols, 65% EGCG) | Improves glycemic control | Mixed, modest results. NCCIH notes rare liver injury from concentrated green tea extracts. |
| Cinnamon (cassia) bark | Enhances insulin sensitivity, suppresses appetite | NCCIH says it is unclear whether cinnamon helps diabetes; cassia contains coumarin, a concern for people with liver disease. |
| Gymnema sylvestre leaf | Blocks sweet taste, supports glucose levels | Gymnema dulls sweet taste when it touches the tongue; a swallowed capsule does not. Small glucose studies exist; evidence is limited. |
| Theacrine (TeaCrine®) | Supports glucose metabolism, focus and energy | A caffeine-like compound studied for energy and mood; we found no good human evidence for blood sugar. |
| Theobromine, eleuthero root | Not described on the sales page | Theobromine is the mild stimulant in cocoa; eleuthero is a traditional "adaptogen". Neither has solid blood sugar evidence. |

Two things stand out. The seven blend ingredients share 525 mg, so there is no way to know whether you get a meaningful dose of cinnamon or gymnema, which were usually studied at hundreds of milligrams to grams a day. And the chromium dose is high: 1,000 mcg against a daily value of 35 mcg. That is within the range used in studies, and the FAQ itself warns against stacking Gluco6 with other chromium-rich formulas, so check any multivitamin you take.
Every ingredient, up close
Here is every active ingredient on the label, what it actually is, and what research does and does not show.

Chromium (as chromium niacinate)
1 mgAn essential trace mineral (pictured: broccoli, a common food source of chromium). NCCIH summarizes a 2022 review of 16 studies with 868 people with type 2 diabetes that suggested chromium may improve HbA1c, fasting glucose and insulin resistance, but calls the evidence weak because the studies were small and varied. At 1 mg (1,000 mcg), about 28 times the Daily Value, the dose is within the range used in studies, which is also why the FAQ warns against stacking Gluco6 with other chromium products; most people in the US are not deficient, so any benefit is likely modest.
Photo: David / Public domain, via Wikimedia Commons
Vitamin D3
50 mcg (2,000 IU)The form of vitamin D the skin makes in sunlight (pictured: salmon fillet, a common food source of vitamin D). It is useful if your level is low, but in diabetes reviews the effect on blood sugar was small and below what doctors consider meaningful. 2,000 IU is above the 600 to 800 IU recommended daily amount and below the 4,000 IU upper limit the NIH sets for adults, so count any other vitamin D you take.
Photo: Tiia Monto / CC BY-SA 3.0, via Wikimedia Commons
Vitamin B1 (thiamine)
100 mgVitamin B1, which the body needs to turn carbohydrates into energy (pictured: sunflower seeds, a common food source of thiamine). 100 mg is many times the roughly 1.2 mg adults need a day; there is no good evidence that extra thiamine lowers blood sugar in people who are not deficient.
Photo: Dmitry Makeev / CC BY-SA 4.0, via Wikimedia CommonsSukre (L-arabinose)
In a 525 mg blend, amount not disclosedA plant sugar, sold as Sukre, that slows the enzyme that digests table sugar; it is the "bizarre type of sugar" in the ads. The small Japanese study the brand cites found a smaller glucose rise when L-arabinose was mixed into a sucrose-containing food, and the other study it cites was in rats. Timing is the catch: a capsule before a low-sugar breakfast will do little for the cake you eat at 4 p.m., and its share of the 525 mg blend is not disclosed.

Green tea extract (98% polyphenols, 65% EGCG)
In a 525 mg blend, amount not disclosedA concentrated extract of Camellia sinensis leaves (98% polyphenols, 65% EGCG). Results for blood sugar control are mixed and modest, NCCIH notes rare liver injury from concentrated green tea extracts, and it can lower blood levels of drugs such as nadolol and atorvastatin.

Cinnamon (cassia) bark
In a 525 mg blend, amount not disclosedCassia is the common, inexpensive type of cinnamon. A 2019 review of 16 studies found lower fasting glucose and insulin resistance in prediabetes and type 2 diabetes, but the studies used different types and doses, usually hundreds of milligrams to grams a day, and NCCIH concludes it is unclear whether cinnamon helps. Cassia contains coumarin, which matters for people with liver disease, and there is no way to tell how much of the 525 mg blend is cinnamon.
Photo: NanaYawBotar / CC BY-SA 4.0, via Wikimedia Commons
Gymnema sylvestre leaf
In a 525 mg blend, amount not disclosedA climbing plant from India known as gurmar, "sugar destroyer". It dulls sweet taste when the leaf touches your tongue; a swallowed capsule bypasses the tongue, so the "blocks cravings" claim hardly applies. Small glucose studies exist, mostly at hundreds of milligrams of extract a day, and the evidence is limited.
Photo: Satheesan.vn / CC BY-SA 3.0, via Wikimedia CommonsTheacrine (TeaCrine)
In a 525 mg blend, amount not disclosedA caffeine-like compound found in a Chinese tea plant, sold as TeaCrine. It has been studied for energy and mood; we found no good human evidence for blood sugar, and it is one reason the "no stimulants" badge is misleading.

Theobromine
In a 525 mg blend, amount not disclosedThe mild stimulant in cocoa and dark chocolate (pictured: cocoa beans, its natural source). Gentler than caffeine, but still a stimulant, with no solid blood sugar evidence.
Photo: Mikkel Houmøller / CC BY-SA 4.0, via Wikimedia Commons
Eleuthero root
In a 525 mg blend, amount not disclosedAlso called Siberian ginseng, a traditional "adaptogen" root from northeast Asia. Studies on fatigue are mixed, and there is no solid blood sugar evidence.
Photo: Maša Sinreih in Valentina Vivod / CC BY-SA 3.0, via Wikimedia CommonsHow Gluco6 is supposed to work
The sales story is built around "GLUT-4 Overwhelm". GLUT4 is real: it is the transporter that lets muscle and fat cells take in glucose when insulin signals them. But "GLUT-4 Overwhelm" is not a medical diagnosis. What the page describes in dramatic terms is insulin resistance, which doctors treat with diet, activity, weight loss and medicines like metformin. The formula attacks it from several angles (chromium for insulin action, L-arabinose to slow sugar digestion, cinnamon and gymnema for glucose), plus theacrine and theobromine for energy. It is a reasonable mix, but the effects in research were small.
Check Gluco6 price on the official site →Opens the brand's official website · money-back guarantee
How to take Gluco6
The label says one capsule a day; the FAQ adds "in the morning before breakfast with a glass of water". If you take diabetes medicine, ask your doctor first and check your glucose more often in the first weeks. Because of the theacrine and theobromine, avoid taking it late in the day. Do not take more than one capsule.
How much does Gluco6 cost?
The official order page sells three packages, each a single charge. The FAQ states there is no auto-ship, no subscription and no hidden charges.
2 bottles60-day supply$69 /bottle$138 · + $9.95 US shippingCheck availability →Best value
6 bottles180-day supply$39 /bottle$234 · free shipping + 2 e-booksCheck availability →
3 bottles90-day supply$49 /bottle$147 · free US shipping + 2 e-booksCheck availability →| Package | Supply | Price per bottle | Total | Extras |
|---|---|---|---|---|
| 2 bottles | 60-day supply | $69 | $138 | + $9.95 US shipping |
| 6 bottles | 180-day supply | $39 | $234 | free shipping + 2 e-books |
| 3 bottles | 90-day supply | $49 | $147 | free US shipping + 2 e-books |
Prices as listed on the official order page when we checked. They change from time to time, so the checkout page is the final word.
About shipping and extras: the 2-bottle package adds $9.95 US shipping ($19.95 elsewhere); 3 bottles ship free in the US ($19.95 outside it) and the 6-bottle package lists free shipping. The 3 and 6-bottle packages include two digital e-books, Neuro Nourish and Sweetly Slim. A single bottle is not on the main price table; it shows up at $48.30 (30% off $69) only in an exit pop-up. The FAQ says orders ship within 24 working hours and arrive in 5 to 10 days in the US.
How the 60-day guarantee works

Every order from the official Gluco6 store is covered by a 60-day money-back guarantee, and it is a one-time payment with no subscription or auto-shipment.
You have 60 days. The FAQ says you can return the bottles "even if empty", and the returns page says opened and unopened bottles are accepted with all labels attached. Open a refund ticket at helpdesk.gluco6.com or call the order line at 302-200-3480, then ship the bottles to 19655 E 35th Drive, Suite 100, Aurora, CO 80011. Two things to know:
- You pay return shipping, and the FAQ says the refund is "less shipping and handling fees", so the original shipping charge is not refunded.
- The returns page asks you to allow at least seven working days after the bottles arrive for the refund to be processed. Send them well before day 60.
Who should talk to a doctor before taking Gluco6?
- Anyone taking insulin or a sulfonylurea (glipizide, glyburide, glimepiride): adding chromium, gymnema, cinnamon and L-arabinose could push blood sugar too low. Ask your doctor first and check your glucose more often.
- Anyone on metformin, GLP-1 drugs or other diabetes medicine: the risk of lows is smaller with some of these, but the combination still needs your doctor's input. Do not lower or stop any diabetes medicine on your own.
- People with kidney or liver disease: high-dose chromium has been linked to rare kidney and liver problems, green tea extract to rare liver injury, and cassia cinnamon contains coumarin.
- Anyone sensitive to caffeine, or with anxiety, insomnia, a fast or irregular heartbeat or high blood pressure: theacrine, theobromine and green tea extract are stimulant-type ingredients, despite the "no stimulants" badge.
- Anyone taking heart, blood pressure or cholesterol medicine: green tea extract can lower blood levels of some drugs, such as nadolol and atorvastatin.
- Pregnant or nursing women and anyone under 18: the label itself says it is not for them.
Possible side effects include stomach upset, jitteriness or poor sleep. Stop and get advice if you feel shaky, sweaty or confused, which can be signs of low blood sugar.
What to realistically expect
The sales page promises 20 to 30 pounds of weight loss and features a customer who says he "ditched all my meds". None of that is supported by the research on these ingredients, which found small changes in glucose markers over weeks to months. A fair test is to get an A1C or fasting glucose result first, take one capsule a day for eight to ten weeks without changing anything else, and then repeat the test with your doctor. If nothing has moved, use the guarantee before day 60.
Our verdict
Gluco6 deserves credit for showing its label, keeping the routine to one capsule and offering a refund that accepts opened bottles. Its formula leans on chromium, cinnamon, gymnema and L-arabinose, ingredients with some but weak evidence for blood sugar, and it hides the herb doses inside a blend. The marketing oversells it badly, and it can add to the effect of diabetes medicines. If your doctor is on board and you want a modest supplement alongside diet and activity, it is a reasonable option to try from the official site.
Check Gluco6 price on the official site →Opens the brand's official website · money-back guarantee
Your doubts, answered honestly
Is Gluco6 a scam?
Verifiable: a Supplement Facts label on the order page (marked "sample", so compare it with your bottle), a returns address in Aurora, Colorado, an order line at 302-200-3480, a ticket helpdesk, one-time payments and a 60-day refund that accepts opened bottles. Not credible: the sales page's 20 to 30 pounds of weight loss and the customer who "ditched all my meds". The product is real; parts of the marketing are not.
Why does it cost $39 to $69 a bottle?
One capsule a day means one bottle lasts 30 days: about $1.30 a day on the 6-bottle package and about $2.30 a day on the 2-bottle package, plus $9.95 shipping on that one. You get a high chromium dose, vitamins D3 and B1 and a 525 mg herbal blend in one capsule. Single-ingredient chromium, vitamin D or cinnamon supplements are usually much cheaper, so if you only want one of them, buying it alone costs less.
Will Gluco6 work for me?
Research on these ingredients found small changes in glucose markers over weeks to months, not the dramatic results in the ads. A fair test is to get an A1C or fasting glucose result, take one capsule a day for eight to ten weeks without changing anything else, and retest with your doctor. People whose blood sugar is already well controlled, or who are not low in chromium or vitamin D, are the least likely to notice anything.
Is it safe? Can I take it with my medication?
Chromium, gymnema, cinnamon and L-arabinose all aim at blood sugar, so with insulin or a sulfonylurea they could push it too low; with metformin or GLP-1 drugs, your doctor should still weigh in. Never lower a diabetes medicine on your own. Theacrine, theobromine and green tea extract are stimulant-type ingredients, cassia contains coumarin, high-dose chromium has rare kidney and liver reports, and green tea extract can lower levels of drugs such as nadolol and atorvastatin. Not for pregnant or nursing women or anyone under 18.
What if it doesn't work for me?
You have 60 days, and the FAQ says you can return bottles even if empty, opened or unopened, with labels attached. Open a ticket at helpdesk.gluco6.com or call 302-200-3480, then ship to the Aurora, Colorado address. You pay return shipping, the refund is less shipping and handling, and processing takes at least seven working days after the bottles arrive, so send them well before day 60.
Why not just buy it on Amazon?
Amazon is not listed by the brand as an authorized seller, and the 60-day refund applies to orders placed on the official site. We cannot vouch for listings elsewhere or their return terms.
Do you get paid if I buy?
Yes. We may earn a commission if you buy through our buttons, at no extra cost to you. It does not change the price or our assessment, which is why we call out the overstated claims and the hidden herb doses. The buttons take you to gluco6.com.
Frequently asked questions
What are the ingredients in Gluco6?
The label image on the order page lists chromium 1 mg (as chromium niacinate), vitamin D3 50 mcg, vitamin B1 100 mg and a 525 mg proprietary blend of Sukre prebiotic fiber (L-arabinose), theobromine, green tea extract, eleuthero root, theacrine (TeaCrine), cassia cinnamon and gymnema. The blend does not show the amount of each herb.
How do you take Gluco6?
One capsule a day with water, preferably in the morning before breakfast. Each bottle has 30 capsules, a 30-day supply.
How much does Gluco6 cost?
The order page lists 2 bottles for $138 ($69 each) plus $9.95 US shipping, 3 bottles for $147 ($49 each) and 6 bottles for $234 ($39 each), with free US shipping on 3 and 6. A single bottle at $48.30 appears only in a pop-up when you try to leave the page.
Can I take Gluco6 with metformin or insulin?
Only with your doctor's approval. Chromium, gymnema, cinnamon and L-arabinose all aim to lower blood sugar, so combined with diabetes medicines they could cause lows. Never reduce your medicine on your own.
Does Gluco6 contain caffeine or stimulants?
The page shows a "no stimulants" badge, but the label lists theacrine and theobromine, which are caffeine-like compounds, and green tea extract. If you are sensitive to caffeine, keep that in mind.
Who pays return shipping on Gluco6?
You do. The returns page says the customer is responsible for return shipping, and the FAQ says the refund is less shipping and handling fees.
Related reading
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Buy it from the official store so the guarantee applies, and keep your order email until you decide.
Check Gluco6 price on the official site →Opens the brand's official website · money-back guaranteeSources
- Gluco6 official order page, text version, FAQ, Supplement Facts label image, shipping and returns page, terms and support pages (gluco6.com), accessed October 2026
- NCCIH: Diabetes and Dietary Supplements: What You Need To Know. nccih.nih.gov
- NIDDK: Low Blood Glucose (Hypoglycemia). niddk.nih.gov
- NIH Office of Dietary Supplements: Chromium, Health Professional Fact Sheet. ods.od.nih.gov
- NCCIH: Cinnamon. nccih.nih.gov/health/cinnamon
- NCCIH: Green Tea. nccih.nih.gov/health/green-tea
- Effect of L-Arabinose on Blood Glucose Level after Ingestion of Sucrose-containing Food in Human (cited on the order page). jstage.jst.go.jp
- Protective effects of L-arabinose in high-carbohydrate, high-fat diet-induced metabolic syndrome in rats (cited on the order page). pmc.ncbi.nlm.nih.gov/articles/PMC4676841

